What is hyaluronidase?
Hyaluronidase is used together with fluids injected into the body to treat dehydration. Hyaluronidase can also be use as an aid in helping your body absorb other injected medications. hyaluronidase injection
It’s also used to help contrast dyes in your body show more clearly on certain types of x-rays or scans.
Hyaluronidase may also be used for purposes not listed in this medication guide.
Serious drug interactions can occur when certain medicines are used together with hyaluronidase. Tell your doctor about all your current medicines.
Before taking this medicine
You should not be treated with hyaluronidase if you are allergic to it.
Your doctor may perform a skin test to see if you are allergic to hyaluronidase before you receive the medication.
Some medicines can cause unwanted or dangerous effects when used with hyaluronidase. Your doctor may change your treatment plan if you also use:
- furosemide (Lasix);
- phenytoin (Dilantin);
- a sedative or anxiety medication (such as diazepam, lorazepam, alprazolam, Valium, Xanax, Ativan, Tranxene, and others);
- aspirin or salicylates;
- cortisone or ACTH (Corticotropin);
- estrogens; or
- an antihistamine (such as a cold or allergy medicine).
Tell your doctor if you are pregnant.
It may not be safe to breast-feed while using hyaluronidase. Ask your doctor about any risk.
How is hyaluronidase given?
Hyaluronidase is inject under the skin, into a muscle, or into other tissues of the body.
A healthcare provider will give you this injection.
Hyaluronidase should not be injected into a vein (as an intravenous injection).
What happens if I miss a dose?
Because you will receive hyaluronidase in a clinical setting, you are not likely to miss a dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid after receiving hyaluronidase?
Follow your doctor’s instructions about any restrictions on food, beverages, or activity.
Hyaluronidase side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
swelling in your hands, feet, or other body areas; or
pain, swelling, itching, or redness where the injection was given.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.